Dr. Sperduto's scope of practice includes radiation therapy for a wide range of tumors, with a special interest in brain tumors.
He was past president of XKnife Society (Radiosurgery) and principal investigator of the Radiation Therapy Oncology Group.
Dr. Sperduto was selected as one of the “Top Doctors in the Twin Cities” in Mpls. St. Paul magazine in 2007, 2009 - 2011, 2016 and 2018. In July 2014 he was selected to receive the Fellow of the American Society for Radiation Oncology (ASTRO) designation. Dr. Sperduto was also named "Top Doctor" in Minnesota Monthly in 2018.
He is a member of Ridgeview's Cancer Care Committee.